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Alzheimer's Association | Alzheimer's Disease & Dementia Help
Alzheimer's Association national site – get information on Alzheimer's disease and dementia symptoms, causes, treatment and care. Join the fight to end ALZ.

Alzheimer's disease - Symptoms and causes - Mayo Clinic
Overview Alzheimer's disease is the most common cause of dementia. Alzheimer's disease is the biological process that begins with the appearance of a buildup of proteins in the form of amyloid plaques and neurofibrillary tangles in the brain. This causes brain cells to die over time and the brain to shrink.

Alzheimer's disease - Wikipedia
Alzheimer's disease (AD) is a neurodegenerative disease and is the most common cause of dementia, accounting for around 60–70% of cases. [14][15] The most common early symptom is difficulty in remembering recent events. [1] As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and ...

What is Alzheimer's Disease? Symptoms & Causes | alz.org
Alzheimer's disease is a type of dementia that affects memory, thinking and behavior - learn about causes, symptoms, tests, stages, treatments and more.

What Is Alzheimer’s Disease?
Find information about Alzheimer’s disease causes, signs and symptoms, diagnosis and treatment, and resources.

Alzheimer's Disease Fact Sheet - National Institute on Aging
Alzheimer’s is currently ranked as the seventh leading cause of death in the United States and is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning — thinking, remembering, and reasoning — and behavioral abilities to such an extent that it interferes with a person’s daily life and activities. Dementia ranges in severity from the mildest ...

Alzheimer’s Disease: Symptoms & Treatment - Cleveland Clinic
Alzheimer’s disease risk can pass through generations of a biological family. Learn what causes it and which changes to watch out for.

Alzheimer's disease - NHS
Alzheimer's disease is the most common cause of dementia. Dementia is a group of symptoms associated with a decline in the way your brain functions, affecting your memory and the way you behave.

Alzheimer's Society
Alzheimer’s Society is the UK’s leading dementia charity. We give vital support to those who need it, fund groundbreaking research, and campaign to improve experiences. It will take a society to beat dementia.

About Alzheimer's | Alzheimer's Disease and Dementia | CDC
Alzheimer’s disease is the most common type of dementia. Early symptoms typically appear after age 60, and the risk increases with age. Learn more about Alzheimer's disease, including who it affects, warning signs, and what to do if you think you or a loved one might have it.

* Neurology101 LATEST NEWS *

                    *Filter: "Alzheimers"

Blood Biomarker May Signal Memory Vulnerability Years Before Cognitive Changes  University of Miami
Why Orexin in Alzheimer Disease Demands Targeted Sleep Therapy  EMJ
Blood and Gene Test Combo Forecasts Alzheimer’s Symptoms Years Before Onset  Columbia University Irving Medical Center
World Alzheimer’s Month: How Far Has Science Come? | Newswise  Newswise
Iron, Selenium, and Dementia; Epilepsy and Education; Brain Death Conversations  MedPage Today
Study ties estrogen-based menopausal hormone therapy to lower Alzheimer’s risk  Stanford Medicine
Orexin, Sleep, and Cognition in Alzheimer Disease  Neurology® Journals
Transient multidomain functional improvement in advanced Alzheimer’s disease following high-dose psilocybin-containing mushroom administration: a case report  Frontiers
5 Unexpected Symptoms of Alzheimer’s — and How to Manage Them  Everyday Health
For Alzheimer’s Disease, New Treatments Offer Hope - Early Diagnosis is Key  School of Medicine | University of Utah
Leqembi Iqlik Offers At-Home SC Initiation for Early Alzheimer Disease  Neurology Advisor
Brain atrophy on MRI could help predict Alzheimer’s progression  news-medical.net
Building the Foundation for Earlier Alzheimer Disease Diagnosis  NeurologyLive
Key path to Alzheimer’s-like brain damage starts outside the brain  WashU Medicine
Association of Circulating Vitamin D in Midlife With Increased Tau-PET Burden in Dementia-Free Adults  Neurology® Journals

Common Neurological Symptoms & Warning Signs

Persistent or Sudden Severe Headaches — Onset of unusually intense headaches, sudden thunderclap onset, or chronic pain accompanied by nausea and visual disruptions.
Numbness, Tingling, or Paresthesia — Loss of sensation, burning, or a "pins and needles" feeling in the extremities, often signaling peripheral neuropathy or nerve compression.
Focal Muscle Weakness or Paralysis — Sudden or progressive loss of muscle strength, facial drooping, or difficulty lifting objects, commonly associated with stroke or nerve disorders.
Seizures and Convulsions — Sudden, uncontrolled electrical disturbances in the brain leading to involuntary muscle spasms, loss of consciousness, or brief absence spells.
Vertigo, Dizziness, and Loss of Balance — Sensations of spinning, unsteady gait, or uncoordinated movement (ataxia), pointing toward vestibular or cerebellar dysfunction.
Cognitive Decline and Memory Impairment — Uncharacteristic confusion, difficulty retrieving words, disorientation, or short-term memory loss impacting daily functioning.
Visual Disturbances and Diplopia — Unexplained double vision, temporary loss of vision in one eye, or sudden blurred vision stemming from optic nerve issues or brain lesions.
Dysarthria and Speech Difficulties — Slurred speech, trouble articulating words, or difficulty comprehending spoken language due to motor speech pathway impairment.

Key Milestones in the History of Neurology

Edwin Smith Papyrus (c. 1600 BCE) — The earliest known medical document describing brain anatomy, cranial sutures, and meninges, detailing head trauma cases in ancient Egypt.
Hippocratic Corpus (c. 400 BCE) — Hippocrates challenged mystical beliefs by identifying the brain, rather than the heart, as the seat of human intelligence, sensation, and emotion.
Vesalius and De Humani Corporis Fabrica (1543) — Andreas Vesalius provided detailed anatomical drawings of the human nervous system, correcting centuries of Galenic anatomical errors.
Discovery of Cerebral Localization (1861) — Paul Broca demonstrated localized speech production functions in the frontal lobe through post-mortem studies of aphasic patients.
Establishment of the Neuron Doctrine (1891–1906) — Santiago Ramón y Cajal and Camillo Golgi revealed that the nervous system consists of discrete individual cells rather than a continuous net.
Invention of Electroencephalography (1924) — Hans Berger recorded the first human brain waves (EEG), revolutionizing epilepsy diagnosis and sleep cycle monitoring.
Development of Neuroimaging Techniques (1970s–1980s) — Godfrey Hounsfield developed Computed Tomography (CT) and Raymond Damadian pioneered MRI, transforming non-invasive brain visualization.
Discovery of Neuroplasticity (Late 20th Century) — Researchers demonstrated that the adult brain reorganizes neural pathways in response to learning, environmental changes, and injury recovery.

Current Neurology Research & Breakthroughs

Blood-Based Biomarkers for Early Alzheimer's Detection — Advances in blood tests tracking amyloid and tau levels allow for faster, non-invasive diagnosis before major cognitive decline occurs.
Adaptive Deep Brain Stimulation (aDBS) in Parkinson's — Closed-loop DBS systems now record real-time neural activity to dynamically adjust stimulation, significantly improving motor fluctuations.
Disease-Modifying Gene Therapies for Neurodegeneration — Novel viral vector therapies target genetic root causes to slow progression in rare conditions like Huntington's disease and ALS.
Precision Immunotherapies for Neuromuscular Disorders — Targeted monoclonal antibody treatments offer faster-acting, long-term disease management for autoimmune conditions like Myasthenia Gravis and CIDP.
Brain-Computer Interfaces (BCI) for Paralysis Recovery — High-density microelectrode arrays decode neural intent into real-time digital text and prosthetic movement for spinal cord injury patients.
Neuroinflammation and Microglial Modulation in Stroke — Investigational therapies focusing on microglial activation show promise in minimizing secondary brain injury following acute ischemic events.
Focused Ultrasound (FUS) Blood-Brain Barrier Opening — Non-invasive MRI-guided ultrasound temporarily opens the blood-brain barrier to deliver targeted chemotherapies directly into brain tumors.
Single-Cell RNA Sequencing in Epilepsy Therapeutics — Transcriptomic profiling identifies specific neuronal subpopulations causing drug-resistant seizures, opening pathways for targeted drug design.